Windows 7 Lenovo i5 with intel built-in Intel graphics and (turned off) Nvidia 5400m card, 8gb ram. Think it occasionally crashed before. Win XP compatibility mode not solving it.
I always use Autosave.You are on a laptop, I take it? Something I noticed with AoD 1.07+ when playing on my own laptop: If autosaves are entirely disabled, the game will eventually CTD without warning on an arbitrary date. Activating autosaves even on the least frequent setting prevents that.
... Not sure whether that is applicable in your case. You did not really provide much detail about the situation that led to your crash.