I started a new game today and abandoned it in frustration once I reached about 60 colonists as the workplace filter seems to be majorly screwed. I got really fed up of firing non-specialists from workplaces I'd marked as "specialists only" and then having them desert their posts at grocers and diners whenever a vacancy at the university showed up. Those that graduated then just hung around, working at said grocer and diner despite those being filtered to "non-specialists only", rather than moving to domes right next door with vacancies in their specialism

I was using the "Workplace filter" mod before the update (I disabled it before starting my new game), but the patch broke that too :'(
That said, I really like most aspects of the patch. Not having to recharge my RC Explorer once I've researched Rover AI is great as I always send it across the map to scan then forget about it! Also, unloading excess fuel if you research the tech that cuts fuel requirements is a welcome fix.
I haven't had any problems with rockets, but I did see one colonist stuck and I had to dismantle my RC Transport as it ended up in a dome rather than going round it on its transport route, which is the first time that's ever happened to me. Don't know if that was a result of the patch, or whether I just got unlucky.
Think I'll have a break for a few days before going back to the game and give it time to settle down.