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I think you should if the mods mess with technologies because it's something that was changed in the update, otherwise you should be okay; but I don't know for a fact. Maybe someone who was in the closed beta can shed some light.
 
i dont think you need to unsubscribe, just disable them in the mod manager

the devs stated that they gave a lot of popular modders access to the beta test, that they can start to update their mods before release, so i guess some of the mods will work right after release or shortly after, for example i am petty sure that mods from "choggi" for example will be working