Mysteries and Replayability

[prof_doom]

So, the mysteries are a cool idea. I do have some minor concerns about what happens after we've seen them all.
Obviously, the expansions and packages will add new mysteries, I'm sure.

My question is: is there any randomness / choice consequences to the mysteries?
For example, I'm watching a video with the sphere. Seems to be chaotic neutral thus far, sucks power, freezes stuff.

Can there be another playthrough where it's actively hostile? One where it's friendly?
Can I choose to try and harness it, destroy it, communicate with it?

 

[Blizzard_Haemimont]

Although there are some choices and branching in the mysteries leading to, for example, alternative endings, I don't imagine that the choices alone will be a motivation to go through the whole mystery from start since a significant chunk of the content will still be the same (depends on your completionist mentality, I guess). And the mysteries take quite a while to go through, so starting a fresh new mystery will certainly be more exciting. Since there are quite a lot of them and they take a while to be finished you will not run out of content quickly and there are other incentives to replay the game as well.

On the other hand, if you have "failed" a mystery you will certainly want to replay it.

 

[Wenatchee Willie]

It seems to me the randomness of the tech tree alone, not to mention the variety in maps where you land, will lead to each game being played differently. Also - sponsor, leader