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What are your computer specs?
Try renaming the folder avi to av...that helps in most cases..you may also try lowering your game resolution to 800*600 if it is set on 1024*768 as lower resolutions need lesser system resources.
 
What Publisher version are you using? You can find out by looking at the logos on the CD.
What patch level are you using?
 
If your animations are still moving, but the game clock doesn't advance anymore, then what you have found is a never ending loop in the EU2 game engine.

This, technically, is a program bug. But, to determine if you found a new one, you must give us the version of EU2 you are currently using.

There was a known issue that could cause a never ending loop with the AI sending merchants to CoT's. This was fixed in one of the more recent versions (don't know exactly which one, but at least version 1.07 should contain the fix).

Jan Peter
 
Which is why we need the publisher and patch info before offereing further advice. ;)
 
Try the latest beta patch and see if that helps.
 
Since you also posted that you have finished a Campaign, I see that this does not happen all the time, so is there anything that triggers it? Does it happen often?