Not exactly. A single model in C:S must use a single texture. If the building is really complex, you could try to break it into the main asset and a series of props, or break it into a couple different buildings and import them separately using the sub buildings enabler mod.
But in any case, each individual imported mesh must use one single UV map. If your building can't be broken down into obvious parts for props, then you will have to remap it onto a single UV map.