Hello there! I've been unable to reproduce the issue on my end, but there are a few things we could try.
First of all, I'd like to know if you are getting any crash logs in the "crashes" folder, found in C:\Users\[username]\Documents\Paradox Interactive\Crusader Kings III
If you are, please make a zip of the most recent one and attach it in a message here. Together with that I'd also like you to run DxDiag, click Save Information and attach that .txt file as well, as it would help us know more about your hardware.
Secondly, this sounds to me like the memory issue we adressed in a recent hotfix, so if you could please try again with the latest update available and see if you still get the random crashes.
Thank you beforehand!