I can't really determine what exactly it's going to be but my gut is telling me it's one of the following five options :
1.An europa universalis spin-off which is not Rome, but I say this one is the least likely
2.An europa universalis spin-off that is Rome
3.A new total war esque franchise focussing on either A.Italian Wars B.Thirty Years war C.War of the roses D.Hundred year wars
4.A new game in a new era possibly the Greeks, early roman empire
5.A new game in the area of 1648-1833 to eventually take over the second part of Europa universalis.
Now I'd say 3 or 4 is the most likely, 3 is something I could actually see them doing.