I had deactivated I18n and kept Extra UI Screens active, and the results were still the same..... game sending me back to the desktop!
I had also deactivated DVNZ, along with deactivating I18n, and still was the same result with Extra UI Screens, sending me back to the desktop....... So it cant be either I18n or DVNZ that is causing it. When I deactivate Extra UI Screens, as well as keeping I18n and DVNZ deactivated, the game runs fine without sending me back to the desktop, so its clear the problem (for me anyways!) is the Extra UI Screens mod.
As for the region packs.... Do you have them all, and activated? If so, are you experiencing very long mod loading time delays? As I do...
Plus what mods are you currently running on your game at the mo?
Thanks