The humans (except the Inquisitors) know nothing about vampires. Most think they don't exist. Vampire keep it that way (it's what they call the Masquerade).
Think of the realm map and the vampire world as a Mafia underworld. Chicago is still a city, it still has a mayor, but there are mob families going around trying to control this underworld. Sometimes, some humans try to fight the Mafia (like the Inquisitors try to fight the vampires) but most just don't care or don't think they even exist/are threatening.
So the humans have no clue of what is happening in the realm map of the mod.
Think of the realm map and the vampire world as a Mafia underworld. Chicago is still a city, it still has a mayor, but there are mob families going around trying to control this underworld. Sometimes, some humans try to fight the Mafia (like the Inquisitors try to fight the vampires) but most just don't care or don't think they even exist/are threatening.
So the humans have no clue of what is happening in the realm map of the mod.